Opportunity Information: Apply for RFA FD 23 019

The Development and Maintenance of Human and Animal Food Rapid Response Teams (U2F) grant opportunity (RFA-FD-23-019) is a cooperative agreement program from the U.S. Food and Drug Administration (FDA) within the Department of Health and Human Services. Its central aim is to help state governments build, sustain, and continuously improve Rapid Response Teams (RRTs) that can manage food-related emergencies affecting both human and animal food (often referred to as HAF). The broader intent is to strengthen the national integrated food safety system by making sure federal, state, and local partners can coordinate more seamlessly during outbreaks, contamination events, and other food safety incidents. Clinical trials are not allowed under this funding opportunity, reinforcing that the work is focused on public health preparedness, response operations, and systems improvement rather than clinical research.

At its core, the program is designed to unify and coordinate emergency response efforts across multiple disciplines that have to work together during a real incident. A major emphasis is strengthening the operational link between epidemiology, laboratory functions, and environmental health or regulatory components. In practice, this means encouraging states to ensure that disease investigators, public health labs, and food regulatory or environmental assessment staff are not operating in separate lanes when an event happens. Instead, they are expected to function as an integrated team that can quickly share findings, align investigative steps, and move efficiently from detecting a problem to identifying its source and implementing control measures.

A second major focus is improving state regulatory and surveillance programs for human and animal food protection through standardized incident management approaches. The FOA highlights the use of Incident Command System (ICS) and National Incident Management System (NIMS) principles, along with a Unified Command structure, to support integrated responses to all-hazards HAF emergencies. This points to a strong expectation that funded programs will be able to scale up quickly and manage complex, multi-agency responses using common command and coordination methods. The operational goal is to rapidly identify and remove adulterated or contaminated food from commerce, limit additional exposure, and conduct root cause investigations so that agencies and industry can address underlying problems and prevent recurrence.

Beyond direct response mechanics, the FOA also emphasizes the supporting capabilities that make rapid response sustainable and consistently effective over time. These supporting components include workforce training and exercises, better data sharing across partners, stronger data analysis capacity to support decision-making, and clear communication practices for both internal coordination and external messaging. The program also highlights continuous process improvement, which signals that states are expected not only to respond to incidents but to review performance afterward, document lessons learned, refine procedures, and adopt best practices. The development and dissemination of best practices and other practical resources is framed as part of building national response capacity, meaning improvements are intended to be useful beyond a single state and contribute to a more capable nationwide system.

From an administrative and funding standpoint, this is categorized as a discretionary grant using a cooperative agreement funding instrument, which typically implies more substantial federal involvement than a standard grant. The activity category is listed under agriculture, consumer protection, and food and nutrition, and the assistance listing (CFDA) number is 93.103. Eligibility is limited to state governments, reflecting the program’s role in strengthening state-level infrastructure and coordination with federal and local partners. The opportunity was created on February 2, 2023, with an original closing date of April 14, 2023. The anticipated maximum award amount (award ceiling) is $360,000, with an expectation of up to 25 awards, indicating an intent to support a sizable network of state RRT efforts rather than only a small number of jurisdictions.

Overall, this funding opportunity is about readiness and operational excellence in food safety emergencies: building teams that can work across disciplines, manage incidents under standardized command structures, move quickly to protect the public by getting unsafe products off the market, and then translate investigative findings into prevention strategies. The emphasis on training, communications, data systems, and continuous improvement shows that FDA is looking for programs that can maintain capability over the long term and contribute to a coordinated national approach to human and animal food incident response.

  • The Department of Health and Human Services, Food and Drug Administration in the agriculture, consumer protection, food and nutrition sector is offering a public funding opportunity titled "Development and Maintenance of Human and Animal Food Rapid Response Teams (U2F) Clinical Trials Not Allowed" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.103.
  • This funding opportunity was created on Feb 02, 2023.
  • Applicants must submit their applications by Apr 14, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $360,000.00 in funding.
  • The number of recipients for this funding is limited to 25 candidate(s).
  • Eligible applicants include: State governments.
Apply for RFA FD 23 019

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Renewal-Native American Tribes Outreach, Education, and Training to Enhance Food Safety and FSMA Compliance (U01) Clinical Trial Not Allowed Apply for RFA FD 23 032

Funding Number: RFA FD 23 032
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Renewal-Local Food Producer Outreach, Education and Training to Enhance Food Safety and FDA Food Safety Modernization Act (FSMA) Compliance (U01) Clinical Trial Not Allowed Apply for RFA FD 23 031

Funding Number: RFA FD 23 031
Agency: Department of Health and Human Services, Food and Drug Administration
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Funding Amount: $1,000,000
Vet-LIRN Capacity-Building Project and Equipment Grants (U18) Apply for PAR 23 202

Funding Number: PAR 23 202
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Cooperative Agreement to Support an Evidence-Based Clinical Practice Guideline for the Management of Laparoscopic Abdominal Surgeries (U01) Clinical Trials Not Allowed Apply for RFA FD 23 035

Funding Number: RFA FD 23 035
Agency: Department of Health and Human Services, Food and Drug Administration
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Funding Amount: $2,000,000
Cooperative Agreement to Support an Evidence-Based Clinical Practice Guideline for the Management of Acute Low Back Pain (U01) Clinical Trials Not Allowed Apply for RFA FD 23 034

Funding Number: RFA FD 23 034
Agency: Department of Health and Human Services, Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $2,000,000
Data Standards for Tobacco Research and Scientific Review Phase 2 Apply for RFA FD 24 001

Funding Number: RFA FD 24 001
Agency: Department of Health and Human Services, Food and Drug Administration
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Manufacturing Sector Research Initiative Apply for RFA FD 17 009

Funding Number: RFA FD 17 009
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Cooperative Agreement to Support the Joint Institute for Food Safety and Applied Nutrition, JIFSAN (U19) Apply for RFA FD 17 003

Funding Number: RFA FD 17 003
Agency: Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
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National Laboratory Curriculum Framework Development Apply for RFA FD 17 012

Funding Number: RFA FD 17 012
Agency: Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $3,750,000
Developing Biomarkers for Trastuzumab-induced Cardiotoxicity Apply for RFA FD 17 006

Funding Number: RFA FD 17 006
Agency: Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $140,000
CVM Vet-LIRN Veterinary Diagnostic Laboratory Program (U18) Clinical Trials Apply for PAR 22 063

Funding Number: PAR 22 063
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Implementation of U.S. Food Safety Modernization Act - Identifying, Researching and Implementing Alternative Methods to Expand the Reach Across the Global Supply Chain (U01) - Clinical Trials Not Allowed Apply for RFA FD 24 013

Funding Number: RFA FD 24 013
Agency: Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $500,000
Strengthening Regulatory Systems to Improve Global Food and Medical Product Quality and Safety (U01) Clinical Trials Not Allowed Apply for RFA FD 24 014

Funding Number: RFA FD 24 014
Agency: Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $750,000
Natural History, Clinical Outcome Assessment, and Biomarker Studies of Rare Neurodegenerative Diseases (U01) Clinical Trials Optional Apply for RFA FD 24 024

Funding Number: RFA FD 24 024
Agency: Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $2,000,000
Public Health Regulatory Systems Strengthening - U01 Clinical Trials Not Allowed Apply for RFA FD 24 015

Funding Number: RFA FD 24 015
Agency: Food and Drug Administration
Category: Agriculture, Consumer Protection, Food and Nutrition
Funding Amount: $150,000
National Project to Support and Promote Consistent Implementation of the Regulatory Standards for the Growing, Harvesting, Packing and Holding of Produce for Human Consumption and Produce Regulatory Standards (PRPS) (U2F) -Cooperative Agreements Apply for RFA FD 24 012

Funding Number: RFA FD 24 012
Agency: Food and Drug Administration
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Funding Amount: $1,500,000
Produce Safety Alliance-U01 Clinical Trials Not Allowed Apply for RFA FD 24 018

Funding Number: RFA FD 24 018
Agency: Food and Drug Administration
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FDA OMHHE Health Equity Innovation Award: Enhance Equity Funding Opportunity (U01) Clinical Trials Not Allowed Apply for RFA FD 24 022

Funding Number: RFA FD 24 022
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Funding Amount: $250,000
Identification and Evaluation of Possible Approaches to Addressing Nitrosamine Impurities in Drugs (U01) Here and Clinical Trial Designator - Clinical Trials Not Allowed Apply for RFA FD 24 020

Funding Number: RFA FD 24 020
Agency: Food and Drug Administration
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Strengthening Global Competency and Capacity in Inspectional Approaches for the Oversight of Human and Animal Pharmaceutical Products (U01) Clinical Trials Not Allowed Apply for RFA FD 24 026

Funding Number: RFA FD 24 026
Agency: Food and Drug Administration
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Funding Amount: $150,000

 

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