Opportunity Information: Apply for 23 578

The National Science Foundation (NSF) is offering the Infrastructure Innovation for Biological Research Program (also called the Innovation Program), a discretionary grant opportunity aimed at building or substantially improving research infrastructure that can move modern biology forward. The core idea is to fund projects that create new or greatly enhanced tools, technologies, and methods that help biologists better manipulate, control, analyze, or measure important features of biological systems. The program is housed within NSF's Directorate for Biological Sciences, and it is meant to support infrastructure that is useful across a broad range of biological research areas rather than being limited to a narrow, single-lab use case.

This opportunity is organized around three main programmatic tracks: Bioinformatics, Instrumentation, and Research Methods. While the exact scope of each track is described in the program's area-specific guidance, the overall expectation is that proposed infrastructure should be broadly applicable and enabling, meaning it should help many researchers tackle important fundamental questions in biology. In practical terms, NSF is looking for infrastructure that changes what researchers can do, such as improving the quality, throughput, precision, or accessibility of biological measurements, enabling new types of experiments, or making it possible to integrate and interpret complex biological data in ways that were previously difficult or impractical.

Proposals can advance biological research in one of three ways: by developing entirely novel infrastructure, by significantly redesigning existing infrastructure to make it much more capable or useful, or by adapting existing infrastructure in a new and creative way that transforms how it can be used in biology. Regardless of the approach, projects are expected to connect clearly to one or more biological science questions and demonstrate how the infrastructure will enable scientific progress. A key theme is community impact: the proposed tools or methods should have credible potential to be adopted or used by researchers beyond a single team, lab, or project, strengthening the broader research ecosystem rather than serving only a local need.

From an administrative standpoint, this is an NSF grant (Funding Opportunity Number 23-578) in the Science and Technology and other Research and Development category (CFDA 47.074). Proposals are accepted at any time rather than being tied to a single annual deadline, which gives applicants flexibility in planning and submission. The maximum award amount listed is $800,000, and NSF anticipates making around 40 awards. Eligibility is listed as "Others" with additional eligibility details provided in the full solicitation text, so prospective applicants should verify that their organization type and project team structure align with NSF's specific requirements before moving forward.

Overall, this program is best understood as NSF's investment in the kinds of shared, enabling advances, whether computational, experimental, or methodological, that can unlock new biological discovery for a wider community of scientists.

  • The National Science Foundation in the science and technology and other research and development sector is offering a public funding opportunity titled "Infrastructure Innovation for Biological Research" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 47.074.
  • This funding opportunity was created on Apr 21, 2023.
  • Applicants must submit their applications by Proposals accepted anytime. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $800,000.00 in funding.
  • The number of recipients for this funding is limited to 40 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for 23 578

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