Opportunity Information: Apply for PAR 22 064

The National Institute on Minority Health and Health Disparities (NIMHD), under the National Institutes of Health (NIH), is offering an R01 grant opportunity titled "Patient-Clinician Relationship: Improving Health Outcomes in Populations that Experience Health Care Disparities (Clinical Trial Optional)" (Funding Opportunity Number PAR-22-064). The central aim is to fund innovative research that explains and improves how patient-clinician relationships and communication influence health care processes and outcomes for groups that experience health disparities. The opportunity is built around the idea that the quality of interaction between patients and clinicians (including trust, shared understanding, respect, and communication effectiveness) can shape real outcomes such as adherence, satisfaction, use of preventive services, timely follow-up, care continuity, and ultimately morbidity and mortality, especially in settings where disparities are persistent.

Projects are expected to be multi-disciplinary and multi-level. "Multi-disciplinary" means applicants can integrate perspectives and methods from behavioral science, biology, environmental health, social science, and cultural studies, among others. "Multi-level" means the research can address not only the patient or the clinician in isolation, but also the relationship between them and the broader context that affects that relationship. Examples of levels mentioned include patient, clinician, interpersonal dynamics, and community context. In practice, a competitive application would typically move beyond describing communication problems to testing mechanisms and solutions: for instance, how structural barriers, cultural mismatch, implicit bias, time pressure, language differences, health literacy, digital access, clinic workflow, or community norms affect communication quality, and which strategies measurably improve outcomes for disparity-affected populations.

The funding mechanism is an NIH R01 research project grant, and clinical trials are optional, meaning applicants may propose either observational/mechanistic studies or interventional studies that meet NIH's definition of a clinical trial. The opportunity is categorized as discretionary and falls under a health funding activity category, with CFDA numbers listed as 93.173, 93.307, 93.313, and 93.846. The posting highlights NIMHD's intent to support research that is not only descriptive but also designed to "understand and address" the effects of optimizing relationships and communication, which signals interest in actionable findings, intervention development, or implementation-relevant approaches that can be translated into real-world care improvements.

Eligibility is broad and includes many domestic U.S. organizational types. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with and without 501(c)(3) status (excluding institutions of higher education); for-profit organizations (other than small businesses); and small businesses. The announcement also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, Indian/Native American tribal governments other than federally recognized, and U.S. territories or possessions. This emphasis signals that NIMHD is open to (and may be particularly interested in) proposals that are closely connected to the communities experiencing disparities and that are led by or meaningfully partnered with institutions serving those communities.

At the same time, there are clear restrictions related to foreign involvement. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply. Non-domestic components of U.S. organizations are not eligible to apply. In addition, foreign components, as defined by the NIH Grants Policy Statement, are not allowed. In other words, the applicant organization must be U.S.-based, and the funded work must not include foreign components under NIH policy, which effectively confines the research activities and organizational structures to domestic settings.

The opportunity lists an original closing date of January 7, 2025, and the creation date of the opportunity record is November 16, 2021. An award ceiling is not specified in the provided data, and the expected number of awards is also not listed, which typically means applicants should consult the full funding opportunity announcement and NIH policies for budget expectations, project period norms, and any institute-specific budget guidance. Overall, this R01 is aimed at generating rigorous evidence on how better patient-clinician relationships and communication can be engineered, supported, and sustained in health care environments to reduce disparities and improve outcomes for populations that have historically received inequitable care.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Patient-Clinician Relationship: Improving Health Outcomes in Populations that Experience Health Care Disparities (R01 Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173, 93.307, 93.313, 93.846.
  • This funding opportunity was created on 2021-11-16.
  • Applicants must submit their applications by 2025-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 22 064

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Frequently Asked Questions (FAQs)

1) What is the name of this grant opportunity?

The opportunity is titled "Patient-Clinician Relationship: Improving Health Outcomes in Populations that Experience Health Care Disparities (Clinical Trial Optional)."

2) Who is offering this funding opportunity?

The National Institute on Minority Health and Health Disparities (NIMHD), under the National Institutes of Health (NIH), is offering this grant opportunity.

3) What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is PAR-22-064.

4) What is the main purpose of this grant?

The central aim is to fund innovative research that explains and improves how patient-clinician relationships and communication influence health care processes and outcomes for groups that experience health disparities.

5) What kinds of outcomes is this opportunity interested in?

The opportunity highlights outcomes that can be shaped by patient-clinician interaction quality, including adherence, satisfaction, use of preventive services, timely follow-up, continuity of care, and ultimately morbidity and mortality, especially where disparities persist.

6) What does the opportunity mean by "patient-clinician relationship" and "communication"?

The posting emphasizes the quality of interaction between patients and clinicians, including trust, shared understanding, respect, and communication effectiveness, and how these factors can influence care processes and health outcomes.

7) What funding mechanism is being used?

This is an NIH R01 research project grant opportunity.

8) Are clinical trials required?

No. Clinical trials are optional. Applicants may propose observational or mechanistic studies, or interventional studies that meet NIH's definition of a clinical trial.

9) What type of research approaches are encouraged?

The opportunity is geared toward research that is multi-disciplinary and multi-level, and that moves beyond describing communication problems to testing mechanisms and solutions that can improve outcomes in populations experiencing health care disparities.

10) What does "multi-disciplinary" mean in this context?

11) What does "multi-level" mean in this context?

"Multi-level" means research can address multiple layers that affect patient-clinician relationships, not just the patient or clinician alone. Levels mentioned include the patient, the clinician, interpersonal dynamics, and the surrounding community context.

12) What kinds of factors could an application examine?

Examples described include structural barriers, cultural mismatch, implicit bias, time pressure, language differences, health literacy, digital access, clinic workflow, and community norms, and how these factors affect communication quality and outcomes.

13) Is NIMHD looking for descriptive studies only?

No. The posting signals interest in studies designed to "understand and address" the effects of optimizing relationships and communication, suggesting a preference for actionable findings such as intervention development, testing, or implementation-relevant approaches.

14) What does "discretionary" mean for this opportunity?

The opportunity is categorized as discretionary in the provided information, and it falls under a health funding activity category.

15) What are the CFDA numbers associated with this opportunity?

The CFDA numbers listed are 93.173, 93.307, 93.313, and 93.846.

16) Who is eligible to apply?

Eligibility is broad for domestic U.S. organizational types. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with and without 501(c)(3) status (excluding institutions of higher education); for-profit organizations (other than small businesses); and small businesses.

17) Are community-based or faith-based organizations eligible?

Yes. The announcement explicitly includes faith-based or community-based organizations among the highlighted eligible applicant categories.

18) Are Minority Serving Institutions (MSIs) specifically mentioned?

Yes. The announcement explicitly highlights Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and other institutions serving communities that experience disparities.

19) Are U.S. territories or possessions eligible to apply?

Yes. The opportunity information explicitly mentions U.S. territories or possessions as eligible applicant categories.

20) Are federal agencies eligible to apply?

Yes. Eligible federal agencies are explicitly included among the highlighted eligible applicant categories.

21) Are foreign (non-U.S.) organizations eligible to apply?

No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply.

22) Can a U.S. organization apply if it has a non-domestic component?

No. Non-domestic components of U.S. organizations are not eligible to apply, based on the information provided.

23) Are "foreign components" allowed in the project?

No. Foreign components, as defined by the NIH Grants Policy Statement, are not allowed under this opportunity.

24) Does this mean the funded research must be conducted domestically?

Based on the stated restrictions (no foreign institutions, no non-domestic components, and no foreign components), the work is effectively confined to domestic settings under NIH policy.

25) What is the closing date listed for this opportunity?

The information provided lists an original closing date of January 7, 2025.

26) When was the opportunity record created?

The creation date of the opportunity record is November 16, 2021.

27) Is there an award ceiling (maximum award amount) listed?

No. An award ceiling is not specified in the provided information.

28) Is the expected number of awards listed?

No. The expected number of awards is not listed in the provided information.

29) What does it imply if the award ceiling and number of awards are not provided?

It typically means applicants may need to consult the full funding opportunity announcement and NIH policies for budget expectations, project period norms, and any institute-specific budget guidance.

30) What would a competitive application generally look like based on the description provided?

Based on the posting, a strong application would typically go beyond documenting communication challenges and instead test mechanisms and solutions. It would likely combine multiple disciplines and address multiple levels (patient, clinician, relationship dynamics, and context), with measurable outcomes tied to health care processes and disparity-relevant impacts.

31) What is the overall focus of the program in one sentence?

The overall focus is to generate rigorous evidence on how patient-clinician relationships and communication can be improved and sustained in real health care environments to reduce disparities and improve outcomes for populations that have historically experienced inequitable care.

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