Opportunity Information: Apply for RFA MH 23 310
This National Institutes of Health (NIH) funding opportunity, RFA-MH-23-310, supports research on how interventions that target social drivers of mental illnesses influence mental health outcomes for young people in low- and middle-income countries (LMICs). The focus is on children, adolescents, and young adults ages 5 through 24 who live in World Bank-designated LMIC settings. Rather than only asking whether an intervention works, the grant is designed to push the field toward answering why and how it works by identifying the specific mechanisms and pathways through which changing social conditions can reduce risk for mental illness or improve mental health and day-to-day functioning.
A central theme of the announcement is real-world complexity. Applicants are expected to use innovative research approaches that can capture the layered and interacting social realities young people face in LMIC contexts. In practice, this means studies should be designed to illuminate the causal chain between a social-driver-focused intervention and mental health outcomes, including intermediate steps, mediators, moderators, and contextual factors that shape impact. The opportunity is oriented toward unpacking processes such as how improvements in safety, stability, social connectedness, school participation, family functioning, or economic conditions translate into changes in symptoms, resilience, functioning, or overall wellbeing for youth. The funding mechanism is an R01, and clinical trials are optional, meaning projects may include a clinical trial component if appropriate, but the announcement does not require one.
The opportunity sits within NIH’s health research mission (CFDA 93.242) and is categorized as a discretionary grant in the health area. The listed award ceiling is $500,000, indicating an upper bound on the amount that can be requested per the terms of the solicitation. The original application due date shown in the source information is February 17, 2023, and the funding notice was created on November 22, 2022, which helps place the timeline and indicates this is a specific, time-bound RFA rather than a permanently open program announcement.
Eligibility is broad and intentionally inclusive, reflecting the kinds of partnerships often needed to study social drivers and interventions at scale. Eligible applicants include multiple levels of government (state, county, city/township, and special district governments), independent school districts, and public housing/Indian housing authorities. Academic institutions are eligible, including public and state-controlled colleges and universities as well as private institutions of higher education. The opportunity is also open to nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education), for-profit organizations (other than small businesses), and small businesses. Tribal entities are explicitly included, such as federally recognized Native American tribal governments and tribal organizations that are not federally recognized governments. In addition, the RFA highlights “other eligible applicants,” naming Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-U.S. entities (foreign organizations). This broad eligibility aligns with the expectation that strong projects may require cross-sector implementation settings and local or regional leadership in LMIC contexts.
Overall, the grant is best understood as a call for mechanism-focused, context-sensitive youth mental health research in LMICs, centered on interventions that address upstream social conditions. Competitive proposals would be expected to go beyond simple outcome evaluation to map and test the pathways linking social change to mental health and functioning, using designs and measures capable of reflecting real-life environments where social drivers operate and where youth development unfolds.Apply for RFA MH 23 310
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Social Drivers of Mental Illnesses in Low- and Middle-Income Countries: Mechanisms and Pathways of Interventions for Youth (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242.
- This funding opportunity was created on 2022-11-22.
- Applicants must submit their applications by 2023-02-17. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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